Results.

The study had 621 participants. The results are summarized in Table 1, which shows a substantial and highly statistically significant reduction in antibiotic exposure.

Table 1. Summary of Results

Summary	Procalcitonin n = 307	Controls n = 314
Outcome • Mortality • LOS (median)	21% 28 days	20% 26 days
Antibiotic exposure • Rate/1000 days • Duration of antibiotics (mean)	653 10.3 days	812 13.3 days

Conclusion. The investigators concluded that procalcitonin-guided decisions for suspected bacterial infections in patients in medical intensive care units can reduce antibiotic exposure without apparent adverse consequences